Introduction
By the end of this assignment, you will be able to apply principles of pharmacokinetics and pharmacodynamics in the selection of drugs to treat health problems. (CO1)
Assignment Guidelines
Answer the question for each case study.
Case Study 1: Dosing Frequency
After learning about pharmacokinetics, Rita realizes the complexity of the interactions between the body and medications. Today, an athlete expressed concern to Rita about the frequency of one of his medications. He was recently prescribed the antibiotic amoxicillin for an upper respiratory tract infection. The antibiotic needs to be taken 3 times per day, and the athlete is having trouble remembering to take it. He asks Rita why the antibiotic has to be taken multiple times per day.
Question: Use a medication reference to review the pharmacokinetics of amoxicillin. Based on the pharmacokinetic and pharmacodynamic parameters, what factor would be most involved in the frequency of dosing?
Case Study 2: Exercise Effect on Insulin
One of the athletes Rita works with has recently been diagnosed with diabetes. The athlete will be using insulin to control his blood sugar and will be injecting the insulin subcutaneously in the thigh. Rita is concerned about the effects that exercise will have on the activity of the insulin and the patient’s blood sugar.
Question: Based on pharmacokinetic and pharmacodynamic principles, what possible effect could exercise have on the insulin?
Please write following APA format and cite your references using APA style.
NOTE TO WRITER: THE LESSON IS “APPLYING PRINCIPLES OF PHARMACOKINETICS AND PHARMACODYNAMICS IN DRUG SELECTION”
Learning Outcomes
At the end of this lesson, you will be able to:
• Describe principles of pharmacokinetics and pharmacodynamic. (CO1)
• Apply principles of pharmacokinetics and pharmacodynamics in the selection of drugs to treat health problems. (CO1)
Learning Materials
Before attempting to complete your learning activities for this week, review the following learning materials:
Read the following in your Pharmacotherapeutics for Advanced Practice Nurse Prescribers textbook:
• Chapter 2, “Review of Basic Principles of Pharmacology”
• Chapter 3, “Rational Drug Selection”
THE BOOK BEING USED IN THE CLASS IS BELOW:
Woo, T. M., & Robinson, M. V. (2020). Pharmacotherapeutics for advanced practice nurse prescribers (5th ed.). F.A. Davis Company.
RUBRIC
ase Study Rubric
Criterion Exceeds Expectations (>4 to 5 Points)
Content Follows all directions, answers all questions thoroughly with examples from experience or literature where appropriate.
Grasp of Significance Projects thorough knowledge and critical understanding of the significance of assignment to professional development as an FNP.
Evidence and Documentation Provides thorough explanation of rationales and skillfully selects resources to substantiate.
Terminology Uses appropriate terminology correctly throughout the entire assignment.
Structure and Mechanics Contains no spelling or grammatical errors. Follows APA formatting criteria. No APA errors.
Total 25 Points