A MINORITY OF CANCER MUTATIONS ARE THOUGHT TO BE “DRIVERS,” DEFINED AS MUTATIONS INVOLVED IN THE DEVELOPMENT OR PROGRESSION OF A TUMOR.
A SUBSET OF THESE DRIVERS AND THEIR COMPONENT CELLULAR PATHWAYS MAY BE “ACTIONABLE”. WHAT IS IT MEANT? A) THE DRIVER MUTATION HAS SIGNIFICANT DIAGNOSTIC IMPLICATIONS B) THE DRIVER MUTATION HAS SIGNIFICANT PROGNOSTIC IMPLICATIONS C) THE DRIVER MUTATION HAS SIGNIFICANT DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS D) THE DRIVER MUTATION HAS LIMITED DIAGNOSTIC IMPLICATIONS E) THE DRIVER MUTATION HAS LIMITED DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS
A minority of cancer mutations are thought to be “drivers,” defined as mutations involved in the development or progression of a tumor. A subset of these drivers and their component cellular pathways may be “actionable”. What is it meant? a) The driver mutation has significant diagnostic implications b) The driver mutation has significant prognostic implications c) The driver mutation has significant diagnostic and therapeutic implications d) The driver mutation has limited diagnostic implications e) The driver mutation has limited diagnostic and therapeutic implications
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