A PATIENT RECEIVED 17 GY IN 2 EQUAL FRACTIONS OVER ONE WEEK TO THE MIDPLANE OF THE CHEST FOR LUNG CANCER
a) A patient received 17 Gy in 2 equal fractions over one week to the
midplane of the chest for lung cancer. Using the linear quadratic
equation, calculate the equivalent total dose at 2Gy per fraction
received by the spinal cord. Assume i) that the spinal cord received
the same total dose as the midplane and ii) that the anterior-posterior
separation was the same throughout the treatment volume. Show the
steps in your calculation.
(2
marks)
b) i) Define accelerated treatment schedules.
ii) List the advantages and disadvantages of accelerated treatment
schedules from a radiobiological point of view.
(4
marks)
c) Draw a labelled diagram of the survival curves of cells from early and
late reacting tissues treated with:
(4
marks)
i) single doses of sparsely ionising radiation and
ii) fractionated sparsely ionising radiation.
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