Write the clinical question use PICO (using the power point of lecture 2) to know how to write the clinical question, Based on the case study provided (find a Randomized Controled Trial paper, apply the appraisal steps on it (uploaded appraisal sheet) 2.

Find the best evidence (do not use Systematic review) use RCT (randomized control trial) Indicate your search strategy (using finding evidence document) please include capture screen shots from where you got the reference (RCT). 3. Evaluate the evidence (using critical appraisal sheet) by answering the questions on that sheet (please use the same sheet and write the answers from that paper you choose-RCT (Randomised Control Trial)- and write your answer on the same sheet).

THERAPY STUDY:

Are the results of the trial valid? (Internal Validity)

What question did the study ask?

Patients –

Intervention –

Comparison –

Outcome(s) –

Did the trial address a clear, focused, and valid question?

Was the assignment of patients to treatments randomised?
What is best? Where do I find the information?
Centralised computer randomisation is ideal and often used in multi-centred trials. Smaller trials may use an independent person (e.g, the hospital pharmacy) to “police” the randomization. The Methods should tell you how patients were allocated to groups and whether or


 

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